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Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli
The genome-scale model (GEM) of metabolism in the bacterium Escherichia coli K-12 has been in development for over a decade and is now in wide use. GEM-enabled studies of E. coli have been primarily focused on six applications: (1) metabolic engineering, (2) model-driven discovery, (3) prediction of...
Autores principales: | McCloskey, Douglas, Palsson, Bernhard Ø, Feist, Adam M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658273/ https://www.ncbi.nlm.nih.gov/pubmed/23632383 http://dx.doi.org/10.1038/msb.2013.18 |
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