SH3 interactome conserves general function over specific form

Src homology 3 (SH3) domains bind peptides to mediate protein–protein interactions that assemble and regulate dynamic biological processes. We surveyed the repertoire of SH3 binding specificity using peptide phage display in a metazoan, the worm Caenorhabditis elegans, and discovered that it structu...

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Detalles Bibliográficos
Autores principales: Xin, Xiaofeng, Gfeller, David, Cheng, Jackie, Tonikian, Raffi, Sun, Lin, Guo, Ailan, Lopez, Lianet, Pavlenco, Alevtina, Akintobi, Adenrele, Zhang, Yingnan, Rual, Jean-François, Currell, Bridget, Seshagiri, Somasekar, Hao, Tong, Yang, Xinping, Shen, Yun A, Salehi-Ashtiani, Kourosh, Li, Jingjing, Cheng, Aaron T, Bouamalay, Dryden, Lugari, Adrien, Hill, David E, Grimes, Mark L, Drubin, David G, Grant, Barth D, Vidal, Marc, Boone, Charles, Sidhu, Sachdev S, Bader, Gary D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658277/
https://www.ncbi.nlm.nih.gov/pubmed/23549480
http://dx.doi.org/10.1038/msb.2013.9

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