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Hepatitis C as a potential cause of IgA nephropathy
This is a case report of a 16-year-old boy presenting with a history of oliguria and anasarca. Workup revealed marked proteinuria to the tune of 8 g/day. He was subsequently found to be hepatitis C positive. Genotype was hepatitis C virus type 6. Renal biopsy revealed mesangioproliferative glomerulo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658295/ https://www.ncbi.nlm.nih.gov/pubmed/23716924 http://dx.doi.org/10.4103/0971-4065.109443 |
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author | Dey, A. K. Bhattacharya, A. Majumdar, A. |
author_facet | Dey, A. K. Bhattacharya, A. Majumdar, A. |
author_sort | Dey, A. K. |
collection | PubMed |
description | This is a case report of a 16-year-old boy presenting with a history of oliguria and anasarca. Workup revealed marked proteinuria to the tune of 8 g/day. He was subsequently found to be hepatitis C positive. Genotype was hepatitis C virus type 6. Renal biopsy revealed mesangioproliferative glomerulonephritis with IgA deposits consistent with IgA nephropathy (IgAN). Initiation of oral ribavirin and pegylated interferon caused a marked reduction in proteinuria after 8 weeks of treatment. It was postulated that hepatitis C manifested as IgAN. This case report thus sheds light on the possibility of an association between hepatitis C and IgAN. |
format | Online Article Text |
id | pubmed-3658295 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-36582952013-05-28 Hepatitis C as a potential cause of IgA nephropathy Dey, A. K. Bhattacharya, A. Majumdar, A. Indian J Nephrol Case Report This is a case report of a 16-year-old boy presenting with a history of oliguria and anasarca. Workup revealed marked proteinuria to the tune of 8 g/day. He was subsequently found to be hepatitis C positive. Genotype was hepatitis C virus type 6. Renal biopsy revealed mesangioproliferative glomerulonephritis with IgA deposits consistent with IgA nephropathy (IgAN). Initiation of oral ribavirin and pegylated interferon caused a marked reduction in proteinuria after 8 weeks of treatment. It was postulated that hepatitis C manifested as IgAN. This case report thus sheds light on the possibility of an association between hepatitis C and IgAN. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3658295/ /pubmed/23716924 http://dx.doi.org/10.4103/0971-4065.109443 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Dey, A. K. Bhattacharya, A. Majumdar, A. Hepatitis C as a potential cause of IgA nephropathy |
title | Hepatitis C as a potential cause of IgA nephropathy |
title_full | Hepatitis C as a potential cause of IgA nephropathy |
title_fullStr | Hepatitis C as a potential cause of IgA nephropathy |
title_full_unstemmed | Hepatitis C as a potential cause of IgA nephropathy |
title_short | Hepatitis C as a potential cause of IgA nephropathy |
title_sort | hepatitis c as a potential cause of iga nephropathy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658295/ https://www.ncbi.nlm.nih.gov/pubmed/23716924 http://dx.doi.org/10.4103/0971-4065.109443 |
work_keys_str_mv | AT deyak hepatitiscasapotentialcauseofiganephropathy AT bhattacharyaa hepatitiscasapotentialcauseofiganephropathy AT majumdara hepatitiscasapotentialcauseofiganephropathy |