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Predicting the probability of H3K4me3 occupation at a base pair from the genome sequence context
Motivation: Histone modifications regulate chromatin structure and gene expression. Although nucleosome formation is known to be affected by primary DNA sequence composition, no sequence signature has been identified for histone modifications. It is known that dense H3K4me3 nucleosome sites are acco...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658463/ https://www.ncbi.nlm.nih.gov/pubmed/23511541 http://dx.doi.org/10.1093/bioinformatics/btt126 |