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Transoral Laser Microsurgery for Early Glottic Cancer

Objectives. To assess the outcome of transoral laser-assisted microsurgery (TLM) with regards to local and distant tumour control, quality of voice and swallowing. Design. Retrospective review of patients with five-year follow-up period. Setting. Royal Derby Hospital Head and Neck Department. Partic...

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Autores principales: McClelland, Lisha, Carr, Esmond, Kamani, Tawakir, Cade, Jennifer, Young, Kate, Mortimore, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658501/
https://www.ncbi.nlm.nih.gov/pubmed/23724259
http://dx.doi.org/10.5402/2011/750676
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author McClelland, Lisha
Carr, Esmond
Kamani, Tawakir
Cade, Jennifer
Young, Kate
Mortimore, Sean
author_facet McClelland, Lisha
Carr, Esmond
Kamani, Tawakir
Cade, Jennifer
Young, Kate
Mortimore, Sean
author_sort McClelland, Lisha
collection PubMed
description Objectives. To assess the outcome of transoral laser-assisted microsurgery (TLM) with regards to local and distant tumour control, quality of voice and swallowing. Design. Retrospective review of patients with five-year follow-up period. Setting. Royal Derby Hospital Head and Neck Department. Participants. All patients undergoing TLM with a diagnosis of Tis, T1, or T2 glottic tumour following endoscopic biopsy. Main Outcome Measures. Speech, swallowing, cancer-free survival, laryngectomy-free survival, and mortality rate. Results. 22 patients were treated for early glottic carcinoma with TLM. The 5-year local control rate for T1 tumours is 89% and 56% for T2 tumours. The laryngectomy rate was 4.5%. The mortality rate from local and distant disease was 4.5% with an overall mortality rate of 22% from all causes. 40% of patients had normal voices and a further 45% had only mild or moderate voice change. At their last followup, no patients assessed had any difficulty swallowing relating to their treatment for glottic cancer. Conclusion. Transoral Endoscopic CO2 laser microsurgery is a valid technique for treating early glottic tumours.
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spelling pubmed-36585012013-05-30 Transoral Laser Microsurgery for Early Glottic Cancer McClelland, Lisha Carr, Esmond Kamani, Tawakir Cade, Jennifer Young, Kate Mortimore, Sean ISRN Otolaryngol Clinical Study Objectives. To assess the outcome of transoral laser-assisted microsurgery (TLM) with regards to local and distant tumour control, quality of voice and swallowing. Design. Retrospective review of patients with five-year follow-up period. Setting. Royal Derby Hospital Head and Neck Department. Participants. All patients undergoing TLM with a diagnosis of Tis, T1, or T2 glottic tumour following endoscopic biopsy. Main Outcome Measures. Speech, swallowing, cancer-free survival, laryngectomy-free survival, and mortality rate. Results. 22 patients were treated for early glottic carcinoma with TLM. The 5-year local control rate for T1 tumours is 89% and 56% for T2 tumours. The laryngectomy rate was 4.5%. The mortality rate from local and distant disease was 4.5% with an overall mortality rate of 22% from all causes. 40% of patients had normal voices and a further 45% had only mild or moderate voice change. At their last followup, no patients assessed had any difficulty swallowing relating to their treatment for glottic cancer. Conclusion. Transoral Endoscopic CO2 laser microsurgery is a valid technique for treating early glottic tumours. International Scholarly Research Network 2011-11-23 /pmc/articles/PMC3658501/ /pubmed/23724259 http://dx.doi.org/10.5402/2011/750676 Text en Copyright © 2011 Lisha McClelland et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
McClelland, Lisha
Carr, Esmond
Kamani, Tawakir
Cade, Jennifer
Young, Kate
Mortimore, Sean
Transoral Laser Microsurgery for Early Glottic Cancer
title Transoral Laser Microsurgery for Early Glottic Cancer
title_full Transoral Laser Microsurgery for Early Glottic Cancer
title_fullStr Transoral Laser Microsurgery for Early Glottic Cancer
title_full_unstemmed Transoral Laser Microsurgery for Early Glottic Cancer
title_short Transoral Laser Microsurgery for Early Glottic Cancer
title_sort transoral laser microsurgery for early glottic cancer
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658501/
https://www.ncbi.nlm.nih.gov/pubmed/23724259
http://dx.doi.org/10.5402/2011/750676
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