Cargando…

Combined proteome and transcriptome analyses for the discovery of urinary biomarkers for urothelial carcinoma

BACKGROUND: Proteomic discovery of cancer biomarkers in body fluids is challenging because of their low abundance in a complex background. Altered gene expression in tumours may not reflect protein levels in body fluids. We have tested combining gene expression profiling of tumours with proteomic an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shimwell, N J, Bryan, R T, Wei, W, James, N D, Cheng, K K, Zeegers, M P, Johnson, P J, Martin, A, Ward, D G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658509/ https://www.ncbi.nlm.nih.gov/pubmed/23591195 http://dx.doi.org/10.1038/bjc.2013.157

Ejemplares similares

Urinary EpCAM in urothelial bladder cancer patients: characterisation and evaluation of biomarker potential
por: Bryan, R T, et al.
Publicado: (2014)

Protein shedding in urothelial bladder cancer: prognostic implications of soluble urinary EGFR and EpCAM
por: Bryan, R T, et al.
Publicado: (2015)

Identification of serum biomarkers for colon cancer by proteomic analysis
por: Ward, D G, et al.
Publicado: (2006)

Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling
por: Atrih, A, et al.
Publicado: (2014)

Expression of parvin-β is a prognostic factor for patients with urothelial cell carcinoma of the upper urinary tract
por: Wu, C-F, et al.
Publicado: (2010)

Preclinical and post-treatment changes in the HCC-associated serum proteome
por: Ward, D G, et al.
Publicado: (2006)

Discovery of serum biomarkers for pancreatic adenocarcinoma using proteomic analysis
por: Xue, A, et al.
Publicado: (2010)

A urinary microRNA signature can predict the presence of bladder urothelial carcinoma in patients undergoing surveillance
por: Sapre, Nikhil, et al.
Publicado: (2016)

Changes in the serum proteome associated with the development of hepatocellular carcinoma in hepatitis C-related cirrhosis
por: Ward, D G, et al.
Publicado: (2006)

MT1-MMP regulates urothelial cell invasion via transcriptional regulation of Dickkopf-3
por: Saeb-Parsy, K, et al.
Publicado: (2008)

Comprehensive profiling and localisation of the matrix metalloproteinases in urothelial carcinoma
por: Wallard, M J, et al.
Publicado: (2006)

In-depth proteomic analysis of tissue interstitial fluid for hepatocellular carcinoma serum biomarker discovery
por: Zhang, Jian, et al.
Publicado: (2017)

Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted
por: Langbein, S, et al.
Publicado: (2006)

Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer
por: Boman, K, et al.
Publicado: (2013)

Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer
por: Anderson, K S, et al.
Publicado: (2011)

Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery
por: Fang, D D, et al.
Publicado: (2010)

Detection of oesophageal cancer biomarkers by plasma proteomic profiling of human cell line xenografts in response to chemotherapy
por: Kelly, P, et al.
Publicado: (2010)

Pre-operative urinary cathepsin D is associated with survival in patients with renal cell carcinoma
por: Vasudev, N S, et al.
Publicado: (2009)

Identification of proteomic biomarkers predicting prostate cancer aggressiveness and lethality despite biopsy-sampling error
por: Shipitsin, M, et al.
Publicado: (2014)

Detection of candidate biomarkers of prostate cancer progression in serum: a depletion-free 3D LC/MS quantitative proteomics pilot study
por: Larkin, S E T, et al.
Publicado: (2016)

Expression of MAGE-A3, NY-ESO-1, LAGE-1 and PRAME in urothelial carcinoma
por: Dyrskjøt, L, et al.
Publicado: (2012)

Diagnostic and mechanistic implications of serum free light chains, albumin and alpha-fetoprotein in hepatocellular carcinoma
por: Teng, M, et al.
Publicado: (2014)

Validation of the pretreatment derived neutrophil–lymphocyte ratio as a prognostic factor in a European cohort of patients with upper tract urothelial carcinoma
por: Dalpiaz, O, et al.
Publicado: (2014)

Serum total hCGβ level is an independent prognostic factor in transitional cell carcinoma of the urothelial tract
por: Douglas, J, et al.
Publicado: (2014)

Identification of macrophage migration inhibitory factor and human neutrophil peptides 1–3 as potential biomarkers for gastric cancer
por: Mohri, Y, et al.
Publicado: (2009)

Pre-treatment plasma proteomic markers associated with survival in oesophageal cancer
por: Kelly, P, et al.
Publicado: (2012)

RET rearrangements in post-Chernobyl papillary thyroid carcinomas with a short latency analysed by interphase FISH
por: Unger, K, et al.
Publicado: (2006)

MicroRNA promoter methylation: a new tool for accurate detection of urothelial carcinoma
por: Padrão, Nuno André, et al.
Publicado: (2017)

BAG-1 as a biomarker in early breast cancer prognosis: a systematic review with meta-analyses
por: Papadakis, E S, et al.
Publicado: (2017)

Early diagnosis of bladder cancer through the detection of urinary tyrosine-phosphorylated proteins
por: Khadjavi, A, et al.
Publicado: (2015)

Urinary TIMP-1 and MMP-2 levels detect the presence of pancreatic malignancies
por: Roy, R, et al.
Publicado: (2014)

An evaluation of urinary microRNA reveals a high sensitivity for bladder cancer
por: Miah, S, et al.
Publicado: (2012)

Diabetogenic glucose and insulin concentrations modulate transcriptom and protein levels involved in tumour cell migration, adhesion and proliferation
por: Masur, K, et al.
Publicado: (2011)

Prognostic significance of Bcl-xL expression and efficacy of Bcl-xL targeting therapy in urothelial carcinoma
por: Yoshimine, S, et al.
Publicado: (2013)

Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer
por: Ord, J J, et al.
Publicado: (2005)

Proteomic analysis of stage I primary lung adenocarcinoma aimed at individualisation of postoperative therapy
por: Maeda, J, et al.
Publicado: (2008)

Serum biomarker panels for the diagnosis of gastric adenocarcinoma
por: Ahn, H S, et al.
Publicado: (2012)

Identification of biomarkers for lymph node metastasis in early-stage cervical cancer by tissue-based proteomics
por: Wang, W, et al.
Publicado: (2014)

Carcinoembryonic antigen is the preferred biomarker for in vivo colorectal cancer targeting
por: Tiernan, J P, et al.
Publicado: (2013)

Fetal haemopoiesis marking low-grade urinary bladder cancer
por: Wolk, M, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ch39tfd1l30os9ccppe9m8lchb