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Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise
Our current health research enterprise is painstakingly slow and cumbersome, and its results seldom translate into practice. The slow pace of health research contributes to findings that are less relevant and potentially even obsolete. To produce more rapid, responsive, and relevant research, we pro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658895/ https://www.ncbi.nlm.nih.gov/pubmed/23663660 http://dx.doi.org/10.1186/2001-1326-2-10 |
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author | Riley, William T Glasgow, Russell E Etheredge, Lynn Abernethy, Amy P |
author_facet | Riley, William T Glasgow, Russell E Etheredge, Lynn Abernethy, Amy P |
author_sort | Riley, William T |
collection | PubMed |
description | Our current health research enterprise is painstakingly slow and cumbersome, and its results seldom translate into practice. The slow pace of health research contributes to findings that are less relevant and potentially even obsolete. To produce more rapid, responsive, and relevant research, we propose approaches that increase relevance via greater stakeholder involvement, speed research via innovative designs, streamline review processes, and create and/or better leverage research infrastructure. Broad stakeholder input integrated throughout the research process can both increase relevance and facilitate study procedures. More flexible and rapid research designs should be considered before defaulting to the traditional two-arm randomized controlled trial (RCT), but even traditional RCTs can be designed for more rapid findings. Review processes for grant applications, IRB protocols, and manuscript submissions can be better streamlined to minimize delays. Research infrastructures such as rapid learning systems and other health information technologies can be leveraged to rapidly evaluate new and existing treatments, and alleviate the extensive recruitment delays common in traditional research. These and other approaches are feasible but require a culture shift among the research community to value not only methodological rigor, but also the pace and relevance of research. |
format | Online Article Text |
id | pubmed-3658895 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Springer |
record_format | MEDLINE/PubMed |
spelling | pubmed-36588952013-05-21 Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise Riley, William T Glasgow, Russell E Etheredge, Lynn Abernethy, Amy P Clin Transl Med Perspective Our current health research enterprise is painstakingly slow and cumbersome, and its results seldom translate into practice. The slow pace of health research contributes to findings that are less relevant and potentially even obsolete. To produce more rapid, responsive, and relevant research, we propose approaches that increase relevance via greater stakeholder involvement, speed research via innovative designs, streamline review processes, and create and/or better leverage research infrastructure. Broad stakeholder input integrated throughout the research process can both increase relevance and facilitate study procedures. More flexible and rapid research designs should be considered before defaulting to the traditional two-arm randomized controlled trial (RCT), but even traditional RCTs can be designed for more rapid findings. Review processes for grant applications, IRB protocols, and manuscript submissions can be better streamlined to minimize delays. Research infrastructures such as rapid learning systems and other health information technologies can be leveraged to rapidly evaluate new and existing treatments, and alleviate the extensive recruitment delays common in traditional research. These and other approaches are feasible but require a culture shift among the research community to value not only methodological rigor, but also the pace and relevance of research. Springer 2013-05-10 /pmc/articles/PMC3658895/ /pubmed/23663660 http://dx.doi.org/10.1186/2001-1326-2-10 Text en Copyright ©2013 Riley et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Perspective Riley, William T Glasgow, Russell E Etheredge, Lynn Abernethy, Amy P Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise |
title | Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise |
title_full | Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise |
title_fullStr | Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise |
title_full_unstemmed | Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise |
title_short | Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise |
title_sort | rapid, responsive, relevant (r3) research: a call for a rapid learning health research enterprise |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658895/ https://www.ncbi.nlm.nih.gov/pubmed/23663660 http://dx.doi.org/10.1186/2001-1326-2-10 |
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