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Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise

Our current health research enterprise is painstakingly slow and cumbersome, and its results seldom translate into practice. The slow pace of health research contributes to findings that are less relevant and potentially even obsolete. To produce more rapid, responsive, and relevant research, we pro...

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Detalles Bibliográficos
Autores principales: Riley, William T, Glasgow, Russell E, Etheredge, Lynn, Abernethy, Amy P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658895/
https://www.ncbi.nlm.nih.gov/pubmed/23663660
http://dx.doi.org/10.1186/2001-1326-2-10
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author Riley, William T
Glasgow, Russell E
Etheredge, Lynn
Abernethy, Amy P
author_facet Riley, William T
Glasgow, Russell E
Etheredge, Lynn
Abernethy, Amy P
author_sort Riley, William T
collection PubMed
description Our current health research enterprise is painstakingly slow and cumbersome, and its results seldom translate into practice. The slow pace of health research contributes to findings that are less relevant and potentially even obsolete. To produce more rapid, responsive, and relevant research, we propose approaches that increase relevance via greater stakeholder involvement, speed research via innovative designs, streamline review processes, and create and/or better leverage research infrastructure. Broad stakeholder input integrated throughout the research process can both increase relevance and facilitate study procedures. More flexible and rapid research designs should be considered before defaulting to the traditional two-arm randomized controlled trial (RCT), but even traditional RCTs can be designed for more rapid findings. Review processes for grant applications, IRB protocols, and manuscript submissions can be better streamlined to minimize delays. Research infrastructures such as rapid learning systems and other health information technologies can be leveraged to rapidly evaluate new and existing treatments, and alleviate the extensive recruitment delays common in traditional research. These and other approaches are feasible but require a culture shift among the research community to value not only methodological rigor, but also the pace and relevance of research.
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spelling pubmed-36588952013-05-21 Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise Riley, William T Glasgow, Russell E Etheredge, Lynn Abernethy, Amy P Clin Transl Med Perspective Our current health research enterprise is painstakingly slow and cumbersome, and its results seldom translate into practice. The slow pace of health research contributes to findings that are less relevant and potentially even obsolete. To produce more rapid, responsive, and relevant research, we propose approaches that increase relevance via greater stakeholder involvement, speed research via innovative designs, streamline review processes, and create and/or better leverage research infrastructure. Broad stakeholder input integrated throughout the research process can both increase relevance and facilitate study procedures. More flexible and rapid research designs should be considered before defaulting to the traditional two-arm randomized controlled trial (RCT), but even traditional RCTs can be designed for more rapid findings. Review processes for grant applications, IRB protocols, and manuscript submissions can be better streamlined to minimize delays. Research infrastructures such as rapid learning systems and other health information technologies can be leveraged to rapidly evaluate new and existing treatments, and alleviate the extensive recruitment delays common in traditional research. These and other approaches are feasible but require a culture shift among the research community to value not only methodological rigor, but also the pace and relevance of research. Springer 2013-05-10 /pmc/articles/PMC3658895/ /pubmed/23663660 http://dx.doi.org/10.1186/2001-1326-2-10 Text en Copyright ©2013 Riley et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Perspective
Riley, William T
Glasgow, Russell E
Etheredge, Lynn
Abernethy, Amy P
Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise
title Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise
title_full Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise
title_fullStr Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise
title_full_unstemmed Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise
title_short Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise
title_sort rapid, responsive, relevant (r3) research: a call for a rapid learning health research enterprise
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658895/
https://www.ncbi.nlm.nih.gov/pubmed/23663660
http://dx.doi.org/10.1186/2001-1326-2-10
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