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Empirical Bayesian analysis of paired high-throughput sequencing data with a beta-binomial distribution
BACKGROUND: Pairing of samples arises naturally in many genomic experiments; for example, gene expression in tumour and normal tissue from the same patients. Methods for analysing high-throughput sequencing data from such experiments are required to identify differential expression, both within pair...
Autores principales: | Hardcastle, Thomas J, Kelly, Krystyna A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658937/ https://www.ncbi.nlm.nih.gov/pubmed/23617841 http://dx.doi.org/10.1186/1471-2105-14-135 |
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