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Quantitative threefold allele-specific PCR (QuanTAS-PCR) for highly sensitive JAK2 V617F mutant allele detection

BACKGROUND: The JAK2 V617F mutation is the most frequent somatic change in myeloproliferative neoplasms, making it an important tumour-specific marker for diagnostic purposes and for the detection of minimal residual disease. Sensitive quantitative assays are required for both applications, particul...

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Detalles Bibliográficos
Autores principales:	Zapparoli, Giada V, Jorissen, Robert N, Hewitt, Chelsee A, McBean, Michelle, Westerman, David A, Dobrovic, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658971/ https://www.ncbi.nlm.nih.gov/pubmed/23617802 http://dx.doi.org/10.1186/1471-2407-13-206

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