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Recombinant Rabies Viruses Expressing GM-CSF or Flagellin Are Effective Vaccines for Both Intramuscular and Oral Immunizations
Our previous studies indicated that recombinant rabies viruses (rRABV) expressing chemokines or cytokines (including GM-CSF) could enhance the immunogenicity by recruiting and/or activating dendritic cells (DC). In this study, bacterial flagellin was cloned into the RABV genome and recombinant virus...
Autores principales: | Zhou, Ming, Zhang, Guoqing, Ren, Guiping, Gnanadurai, Clement W., Li, Zhenguang, Chai, Qingqing, Yang, Yang, Leyson, Christina M., Wu, Wenxue, Cui, Min, Fu, Zhen F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658976/ https://www.ncbi.nlm.nih.gov/pubmed/23700422 http://dx.doi.org/10.1371/journal.pone.0063384 |
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