Clinical Adjuvant Combinations Stimulate Potent B-Cell Responses In Vitro by Activating Dermal Dendritic Cells

CD14(+) dermal DCs (CD14(+) DDCs) have a natural capacity to activate naïve B-cells. Targeting CD14(+) DDCs is therefore a rational approach for vaccination strategies aimed at improving humoral responses towards poorly immunogenic antigens, for example, HIV-1 envelope glycoproteins (Env). Here, we...

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Detalles Bibliográficos
Autores principales: Matthews, Katie, Chung, Nancy P. Y., Klasse, Per Johan, Moutaftsi, Magda, Carter, Darrick, Salazar, André M., Reed, Steven G., Sanders, Rogier W., Moore, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659025/
https://www.ncbi.nlm.nih.gov/pubmed/23700434
http://dx.doi.org/10.1371/journal.pone.0063785

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