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FK-16 Derived from the Anticancer Peptide LL-37 Induces Caspase-Independent Apoptosis and Autophagic Cell Death in Colon Cancer Cells
Host immune peptides, including cathelicidins, have been reported to possess anticancer properties. We previously reported that LL-37, the only cathelicidin in humans, suppresses the development of colon cancer. In this study, the potential anticancer effect of FK-16, a fragment of LL-37 correspondi...
Autores principales: | Ren, Shun X., Shen, Jin, Cheng, Alfred S. L., Lu, Lan, Chan, Ruby L. Y., Li, Zhi J., Wang, Xiao J., Wong, Clover C. M., Zhang, Lin, Ng, Simon S. M., Chan, Franky L., Chan, Francis K. L., Yu, Jun, Sung, Joseph J. Y., Wu, William K. K., Cho, Chi H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659029/ https://www.ncbi.nlm.nih.gov/pubmed/23700428 http://dx.doi.org/10.1371/journal.pone.0063641 |
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