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VIP Gene Deletion in Mice Causes Cardiomyopathy Associated with Upregulation of Heart Failure Genes

RATIONALE: Vasoactive Intestinal Peptide (VIP), a pulmonary vasodilator and inhibitor of vascular smooth muscle proliferation, is absent in pulmonary arteries of patients with idiopathic pulmonary arterial hypertension (PAH). We previously determined that targeted deletion of the VIP gene in mice le...

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Detalles Bibliográficos
Autores principales:	Szema, Anthony M., Hamidi, Sayyed A., Smith, S. David, Benveniste, Helene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659051/ https://www.ncbi.nlm.nih.gov/pubmed/23700405 http://dx.doi.org/10.1371/journal.pone.0061449

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