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RNAi Induces Innate Immunity through Multiple Cellular Signaling Pathways

BACKGROUND & AIMS: Our previous results showed that the knockdown of woodchuck hepatitis virus (WHV) by RNA interference (RNAi) led to upregulation of interferon stimulated genes (ISGs) in primary hepatocytes. In the present study, we tested the hypothesis that the cellular signaling pathways re...

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Detalles Bibliográficos
Autores principales: Meng, Zhongji, Zhang, Xiaoyong, Wu, Jun, Pei, Rongjuan, Xu, Yang, Yang, Dongliang, Roggendorf, Michael, Lu, Mengji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659100/
https://www.ncbi.nlm.nih.gov/pubmed/23700487
http://dx.doi.org/10.1371/journal.pone.0064708

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