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FTY720 postconditions isolated perfused heart by a mechanism independent of sphingosine kinase 2 and different from S1P or ischemic postconditioning

BACKGROUND: We investigated the hypothesis that postconditioning by FTY720 (FTY) in isolated perfused mouse hearts is independent of the sphingosine 1-phosphate (S1P) pathway. MATERIAL/METHODS: Ex vivo hearts were exposed to postconditioning (POST) by either ischemia or FTY720. Protection against is...

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Detalles Bibliográficos
Autores principales:	Vessey, Donald A., Li, Luyi, Imhof, Isabella, Honbo, Norman, Karliner, Joel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2013
Materias:	Animal Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659128/ https://www.ncbi.nlm.nih.gov/pubmed/23567658 http://dx.doi.org/10.12659/MSMBR.883877

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