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What is the impact of electromagnetic waves on epileptic seizures?

BACKGROUND: The effects of electromagnetic waves (EMWs) on humans and their relationship with various disorders have been investigated. We aimed to investigate the effects of exposure to different frequencies of EMWs in various durations in a mouse epilepsy model induced by pentylenetetrazole (PTZ)....

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Detalles Bibliográficos
Autores principales: Cinar, Nilgun, Sahin, Sevki, Erdinc, Oguz O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659130/
https://www.ncbi.nlm.nih.gov/pubmed/23676765
http://dx.doi.org/10.12659/MSMBR.883907
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author Cinar, Nilgun
Sahin, Sevki
Erdinc, Oguz O.
author_facet Cinar, Nilgun
Sahin, Sevki
Erdinc, Oguz O.
author_sort Cinar, Nilgun
collection PubMed
description BACKGROUND: The effects of electromagnetic waves (EMWs) on humans and their relationship with various disorders have been investigated. We aimed to investigate the effects of exposure to different frequencies of EMWs in various durations in a mouse epilepsy model induced by pentylenetetrazole (PTZ). MATERIAL/METHODS: A total of 180 4-week-old male mice weighing 25–30 g were used in this study. Each experimental group consisted of 10 mice. They were exposed to 900, 700, 500, 300, and 100 MHz EMWs for 20 hours, 12 hours and 2 hours. Following electromagnetic radiation exposure, 60 mg/kg of PTZ was injected intraperitoneally to all mice. Each control was also injected with PTZ without any exposure to EMW. The latency of initial seizure and most severe seizure onset were compared with controls. RESULTS: The shortest initial seizure latency was noted in the 12-hour group, followed by the 700 MHz. The mean initial seizure latencies in the 2-hour EMW exposed group was significantly shorter compared to that in the 12- and 20-hour groups. There was no significant difference between 12- and 20-hour EMW exposed groups. There was a significant difference between control and 2- and 10-hour EMW exposed groups. No statistically significant differences were noted in mean latencies of the most severe seizure latency, following 20-, 12-, and 2- hour EMW exposed groups and control groups. CONCLUSIONS: Our findings suggest that acute exposure to EMW may facilitate epileptic seizures, which may be independent of EMW exposure time. This information might be important for patients with epilepsy. Further studies are needed.
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spelling pubmed-36591302013-05-21 What is the impact of electromagnetic waves on epileptic seizures? Cinar, Nilgun Sahin, Sevki Erdinc, Oguz O. Med Sci Monit Basic Res Animal Studies BACKGROUND: The effects of electromagnetic waves (EMWs) on humans and their relationship with various disorders have been investigated. We aimed to investigate the effects of exposure to different frequencies of EMWs in various durations in a mouse epilepsy model induced by pentylenetetrazole (PTZ). MATERIAL/METHODS: A total of 180 4-week-old male mice weighing 25–30 g were used in this study. Each experimental group consisted of 10 mice. They were exposed to 900, 700, 500, 300, and 100 MHz EMWs for 20 hours, 12 hours and 2 hours. Following electromagnetic radiation exposure, 60 mg/kg of PTZ was injected intraperitoneally to all mice. Each control was also injected with PTZ without any exposure to EMW. The latency of initial seizure and most severe seizure onset were compared with controls. RESULTS: The shortest initial seizure latency was noted in the 12-hour group, followed by the 700 MHz. The mean initial seizure latencies in the 2-hour EMW exposed group was significantly shorter compared to that in the 12- and 20-hour groups. There was no significant difference between 12- and 20-hour EMW exposed groups. There was a significant difference between control and 2- and 10-hour EMW exposed groups. No statistically significant differences were noted in mean latencies of the most severe seizure latency, following 20-, 12-, and 2- hour EMW exposed groups and control groups. CONCLUSIONS: Our findings suggest that acute exposure to EMW may facilitate epileptic seizures, which may be independent of EMW exposure time. This information might be important for patients with epilepsy. Further studies are needed. International Scientific Literature, Inc. 2013-05-10 /pmc/articles/PMC3659130/ /pubmed/23676765 http://dx.doi.org/10.12659/MSMBR.883907 Text en © Med Sci Monit, 2013 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License
spellingShingle Animal Studies
Cinar, Nilgun
Sahin, Sevki
Erdinc, Oguz O.
What is the impact of electromagnetic waves on epileptic seizures?
title What is the impact of electromagnetic waves on epileptic seizures?
title_full What is the impact of electromagnetic waves on epileptic seizures?
title_fullStr What is the impact of electromagnetic waves on epileptic seizures?
title_full_unstemmed What is the impact of electromagnetic waves on epileptic seizures?
title_short What is the impact of electromagnetic waves on epileptic seizures?
title_sort what is the impact of electromagnetic waves on epileptic seizures?
topic Animal Studies
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659130/
https://www.ncbi.nlm.nih.gov/pubmed/23676765
http://dx.doi.org/10.12659/MSMBR.883907
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