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Assessing the Quality of Randomized Controlled Urological Trials Conducted by Korean Medical Institutions

PURPOSE: To assess the quality of randomized controlled urological trials conducted by Korean medical institutions. MATERIALS AND METHODS: Quality assessment was conducted by using the Jadad scale; in addition, the van Tulder scale and the Cochrane Collaboration risk of bias tool were used as indivi...

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Autores principales: Chung, Jae Hoon, Lee, Seung Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Urological Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659221/
https://www.ncbi.nlm.nih.gov/pubmed/23700493
http://dx.doi.org/10.4111/kju.2013.54.5.289
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author Chung, Jae Hoon
Lee, Seung Wook
author_facet Chung, Jae Hoon
Lee, Seung Wook
author_sort Chung, Jae Hoon
collection PubMed
description PURPOSE: To assess the quality of randomized controlled urological trials conducted by Korean medical institutions. MATERIALS AND METHODS: Quality assessment was conducted by using the Jadad scale; in addition, the van Tulder scale and the Cochrane Collaboration risk of bias tool were used as individual indices. All assessments were performed by two reviewers. If the outcomes differed, the two reviewers and a third reviewer adjusted the discrepancy in the results through discussion. Starting from 1986, a quality analysis of randomized controlled trials (RCTs) was conducted in 1-year and 5-year units. The quality assessment was conducted by subject, type of intervention, presence of double blinding, presence of funding, and review by an Institutional Review Board (IRB). RESULTS: Whereas the number of RCTs published has gradually increased, there was no significant difference in the quality of the RCTs according to publication year. Drug studies, double-blind studies, studies with funding, and studies reviewed by IRBs had higher quality scores and a higher percentage of high-quality RCTs than did other studies. Thirty-six RCTs were published in journals included in the Science Citation Index and 20 RCTs were published in journals included in the Science Citation Index Expanded. The largest number of RCTs (32.32%) were published by the Korean Journal of Urology. CONCLUSIONS: A quantitative increase was observed in RCTs over time, but no qualitative improvement in the RCTs was observed. It seems necessary to put effort into the quality improvement of RCTs at the design stage.
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spelling pubmed-36592212013-05-22 Assessing the Quality of Randomized Controlled Urological Trials Conducted by Korean Medical Institutions Chung, Jae Hoon Lee, Seung Wook Korean J Urol Special Article PURPOSE: To assess the quality of randomized controlled urological trials conducted by Korean medical institutions. MATERIALS AND METHODS: Quality assessment was conducted by using the Jadad scale; in addition, the van Tulder scale and the Cochrane Collaboration risk of bias tool were used as individual indices. All assessments were performed by two reviewers. If the outcomes differed, the two reviewers and a third reviewer adjusted the discrepancy in the results through discussion. Starting from 1986, a quality analysis of randomized controlled trials (RCTs) was conducted in 1-year and 5-year units. The quality assessment was conducted by subject, type of intervention, presence of double blinding, presence of funding, and review by an Institutional Review Board (IRB). RESULTS: Whereas the number of RCTs published has gradually increased, there was no significant difference in the quality of the RCTs according to publication year. Drug studies, double-blind studies, studies with funding, and studies reviewed by IRBs had higher quality scores and a higher percentage of high-quality RCTs than did other studies. Thirty-six RCTs were published in journals included in the Science Citation Index and 20 RCTs were published in journals included in the Science Citation Index Expanded. The largest number of RCTs (32.32%) were published by the Korean Journal of Urology. CONCLUSIONS: A quantitative increase was observed in RCTs over time, but no qualitative improvement in the RCTs was observed. It seems necessary to put effort into the quality improvement of RCTs at the design stage. The Korean Urological Association 2013-05 2013-05-14 /pmc/articles/PMC3659221/ /pubmed/23700493 http://dx.doi.org/10.4111/kju.2013.54.5.289 Text en © The Korean Urological Association, 2013 http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Article
Chung, Jae Hoon
Lee, Seung Wook
Assessing the Quality of Randomized Controlled Urological Trials Conducted by Korean Medical Institutions
title Assessing the Quality of Randomized Controlled Urological Trials Conducted by Korean Medical Institutions
title_full Assessing the Quality of Randomized Controlled Urological Trials Conducted by Korean Medical Institutions
title_fullStr Assessing the Quality of Randomized Controlled Urological Trials Conducted by Korean Medical Institutions
title_full_unstemmed Assessing the Quality of Randomized Controlled Urological Trials Conducted by Korean Medical Institutions
title_short Assessing the Quality of Randomized Controlled Urological Trials Conducted by Korean Medical Institutions
title_sort assessing the quality of randomized controlled urological trials conducted by korean medical institutions
topic Special Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659221/
https://www.ncbi.nlm.nih.gov/pubmed/23700493
http://dx.doi.org/10.4111/kju.2013.54.5.289
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