IRGM1 regulates oxidized LDL uptake by macrophage via actin-dependent receptor internalization during atherosclerosis

Macrophage derived foam cells are actively involved in the initial phase of atherosclerosis. Uptake of modified lipoprotein such as oxidized LDL (oxLDL) is a critical step for foam cell formation. CD36 is the major receptor mediating oxLDL uptake by macrophage. However, the molecular mechanism under...

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Detalles Bibliográficos
Autores principales: Xia, Fucan, Li, Rui, Wang, Chaodong, Yang, Shuang, Tian, Linlu, Dong, Haiyan, Pei, Chunying, He, Shuyu, Jiang, Pengyu, Cheng, Hairong, Fang, Shaohong, Li, Hulun, Xu, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659323/
https://www.ncbi.nlm.nih.gov/pubmed/23689639
http://dx.doi.org/10.1038/srep01867

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