Evaluation of Adverse Effects of Mutein Forms of Recombinant Human Interferon Alpha-2b in Female Swiss Webster Mice

Purpose. We successfully developed recombinant human interferon alpha-2b (rhIFN-α2b) and mutein forms through the site-directed mutagenesis technique. The mutein forms were developed by substituting cysteins at positions 2 and 99 with aspartic acids. The potential adverse effects of these rhIFN-α2bs...

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Detalles Bibliográficos
Autores principales: Rachmawati, H., Merika, A., Ningrum, R. A., Anggadiredja, K., Retnoningrum, D. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659462/
https://www.ncbi.nlm.nih.gov/pubmed/23738335
http://dx.doi.org/10.1155/2013/943687

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