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Metabolic syndrome in human immunodeficiency virus positive patients

AIMS AND OBJECTIVES: To assess the prevalence of metabolic syndrome (MetS) in human immunodeficiency virus (HIV) positive patients. Prevalence of MetS was compared in patients who were not on highly active antiretroviral therapy (HAART) to patients who were on HAART. MATERIALS AND METHODS: Seventy H...

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Autores principales: Bajaj, Sarita, Tyagi, Susheel Kumar, Bhargava, Anudita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659877/
https://www.ncbi.nlm.nih.gov/pubmed/23776863
http://dx.doi.org/10.4103/2230-8210.107821
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author Bajaj, Sarita
Tyagi, Susheel Kumar
Bhargava, Anudita
author_facet Bajaj, Sarita
Tyagi, Susheel Kumar
Bhargava, Anudita
author_sort Bajaj, Sarita
collection PubMed
description AIMS AND OBJECTIVES: To assess the prevalence of metabolic syndrome (MetS) in human immunodeficiency virus (HIV) positive patients. Prevalence of MetS was compared in patients who were not on highly active antiretroviral therapy (HAART) to patients who were on HAART. MATERIALS AND METHODS: Seventy HIV positive cases were studied. Pregnant and lactating women, patients on drugs other than HAART known to cause metabolic abnormalities and those having diabetes or hypertension were excluded. Cases were evaluated for MetS by using National Cholesterol Education Program Adult Treatment Panel-III. RESULTS: 47 cases were on HAART and 23 cases were not on HAART. Fasting Blood Glucose ≥100 mg/dl was present in 28.6% cases, out of whom 27.7% were on HAART and 30.4% were not on HAART (P = 0.8089). 12.9% cases had BP ≥130/≥85 mm Hg, out of whom 14.9% were on HAART and 8.7% were not on HAART (P = 0.4666). 42.9% cases had TG ≥150 mg/dl, out of whom 44.7% were on HAART and 39.1% were not on HAART (P = 0.6894). HDL cholesterol was low (males <40 mg/dl, females <50 mg/dl) in 50% cases, out of whom 55.3% were on HAART and 39.1% were not on HAART (P = 0.2035). CONCLUSIONS: Prevalence of MetS was 20%. Majority of patients had only one component of MetS (32.9%). Low HDL was present in 50%, followed by raised triglycerides in 42.9%. Waist circumference was not increased in any of the patients. There was no statistically significant difference between those on HAART and those not on HAART in distribution of risk factors and individual components of MetS.
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spelling pubmed-36598772013-06-17 Metabolic syndrome in human immunodeficiency virus positive patients Bajaj, Sarita Tyagi, Susheel Kumar Bhargava, Anudita Indian J Endocrinol Metab Original Article AIMS AND OBJECTIVES: To assess the prevalence of metabolic syndrome (MetS) in human immunodeficiency virus (HIV) positive patients. Prevalence of MetS was compared in patients who were not on highly active antiretroviral therapy (HAART) to patients who were on HAART. MATERIALS AND METHODS: Seventy HIV positive cases were studied. Pregnant and lactating women, patients on drugs other than HAART known to cause metabolic abnormalities and those having diabetes or hypertension were excluded. Cases were evaluated for MetS by using National Cholesterol Education Program Adult Treatment Panel-III. RESULTS: 47 cases were on HAART and 23 cases were not on HAART. Fasting Blood Glucose ≥100 mg/dl was present in 28.6% cases, out of whom 27.7% were on HAART and 30.4% were not on HAART (P = 0.8089). 12.9% cases had BP ≥130/≥85 mm Hg, out of whom 14.9% were on HAART and 8.7% were not on HAART (P = 0.4666). 42.9% cases had TG ≥150 mg/dl, out of whom 44.7% were on HAART and 39.1% were not on HAART (P = 0.6894). HDL cholesterol was low (males <40 mg/dl, females <50 mg/dl) in 50% cases, out of whom 55.3% were on HAART and 39.1% were not on HAART (P = 0.2035). CONCLUSIONS: Prevalence of MetS was 20%. Majority of patients had only one component of MetS (32.9%). Low HDL was present in 50%, followed by raised triglycerides in 42.9%. Waist circumference was not increased in any of the patients. There was no statistically significant difference between those on HAART and those not on HAART in distribution of risk factors and individual components of MetS. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3659877/ /pubmed/23776863 http://dx.doi.org/10.4103/2230-8210.107821 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Bajaj, Sarita
Tyagi, Susheel Kumar
Bhargava, Anudita
Metabolic syndrome in human immunodeficiency virus positive patients
title Metabolic syndrome in human immunodeficiency virus positive patients
title_full Metabolic syndrome in human immunodeficiency virus positive patients
title_fullStr Metabolic syndrome in human immunodeficiency virus positive patients
title_full_unstemmed Metabolic syndrome in human immunodeficiency virus positive patients
title_short Metabolic syndrome in human immunodeficiency virus positive patients
title_sort metabolic syndrome in human immunodeficiency virus positive patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659877/
https://www.ncbi.nlm.nih.gov/pubmed/23776863
http://dx.doi.org/10.4103/2230-8210.107821
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