Paradoxical worsening of seizure activity with pregabalin in an adult with isodicentric 15 (IDIC-15) syndrome involving duplications of the GABRB3, GABRA5 and GABRG3 genes

BACKGROUND: Isodicentric 15 syndrome (IDIC-15) is due to partial duplications of chromosome 15 that may includes the q11–13 region that includes genes encoding the α5 (GABRA5) and β3 - γ3 (GABRB3) receptor subunits. The disease causes intellectual and physical developmental delay, seizures, intellec...

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Detalles Bibliográficos
Autores principales: Di Rocco, Alessandro, Loggini, Andrea, Di Rocco, Maja, Di Rocco, Pietro, Rossi, Roger P, Gimelli, Giorgio, Bazil, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660219/
https://www.ncbi.nlm.nih.gov/pubmed/23663378
http://dx.doi.org/10.1186/1471-2377-13-43

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