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Control of Translation and miRNA-Dependent Repression by a Novel Poly(A) Binding Protein, hnRNP-Q

Translation control often operates via remodeling of messenger ribonucleoprotein particles. The poly(A) binding protein (PABP) simultaneously interacts with the 3′ poly(A) tail of the mRNA and the eukaryotic translation initiation factor 4G (eIF4G) to stimulate translation. PABP also promotes miRNA-...

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Detalles Bibliográficos
Autores principales: Svitkin, Yuri V., Yanagiya, Akiko, Karetnikov, Alexey E., Alain, Tommy, Fabian, Marc R., Khoutorsky, Arkady, Perreault, Sandra, Topisirovic, Ivan, Sonenberg, Nahum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660254/
https://www.ncbi.nlm.nih.gov/pubmed/23700384
http://dx.doi.org/10.1371/journal.pbio.1001564