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Role of p38 and JNK MAPK signaling pathways and tumor suppressor p53 on induction of apoptosis in response to Ad-eIF5A1 in A549 lung cancer cells

BACKGROUND: The eukaryotic translation initiation factor 5A1 (eIF5A1) is a highly conserved protein involved in many cellular processes including cell division, translation, apoptosis, and inflammation. Induction of apoptosis is the only function of eIF5A1 that is known to be independent of post-tra...

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Detalles Bibliográficos
Autores principales: Taylor, Catherine A, Zheng, Qifa, Liu, Zhongda, Thompson, John E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660295/
https://www.ncbi.nlm.nih.gov/pubmed/23638878
http://dx.doi.org/10.1186/1476-4598-12-35