Cargando…

Production of Multiple Transgenic Yucatan Miniature Pigs Expressing Human Complement Regulatory Factors, Human CD55, CD59, and H-Transferase Genes

The present study was conducted to generate transgenic pigs coexpressing human CD55, CD59, and H-transferase (HT) using an IRES-mediated polycistronic vector. The study focused on hyperacute rejection (HAR) when considering clinical xenotransplantation as an alternative source for human organ transp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeong, Young-Hee, Park, Chi-Hun, Jang, Gun-Hyuk, Jeong, Yeun-Ik, Hwang, In-Sung, Jeong, Yeon-woo, Kim, Yu-Kyung, Shin, Taeyoung, Kim, Nam-Hyung, Hyun, Sang-Hwan, Jeung, Eui-Bae, Hwang, Woo-Suk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660325/ https://www.ncbi.nlm.nih.gov/pubmed/23704897 http://dx.doi.org/10.1371/journal.pone.0063241

Ejemplares similares

Amino Acid Supplementation Affects Imprinted Gene Transcription Patterns in Parthenogenetic Porcine Blastocysts
por: Park, Chi-Hun, et al.
Publicado: (2014)

Relative Contribution of Cellular Complement Inhibitors CD59, CD46, and CD55 to Parainfluenza Virus 5 Inhibition of Complement-Mediated Neutralization
por: Li, Yujia, et al.
Publicado: (2018)

Exploring the Genetic Signature of Body Size in Yucatan Miniature Pig
por: Kim, Hyeongmin, et al.
Publicado: (2015)

Specific Acquisition of Functional CD59 but Not CD46 or CD55 by Hepatitis C Virus
por: Ejaz, Asim, et al.
Publicado: (2012)

X-Linked Gene Transcription Patterns in Female and Male In Vivo, In Vitro and Cloned Porcine Individual Blastocysts
por: Park, Chi-Hun, et al.
Publicado: (2012)

Expression of CD55, CD59, and CD35 on red blood cells of β-thalassaemia patients
por: Kurtoǧllu, Ayşegül Uǧur, et al.
Publicado: (2017)

Human immune reactivity of GGTA1/CMAH/A3GALT2 triple knockout Yucatan miniature pigs
por: Shim, Joohyun, et al.
Publicado: (2021)

Expression levels of complement regulatory proteins (CD35, CD55 and CD59) on peripheral blood cells of patients with chronic kidney disease
por: Eldewi, Dalia Mahmoud, et al.
Publicado: (2019)

Altered Expression of Complement Regulatory Proteins CD35, CD46, CD55, and CD59 on Leukocyte Subsets in Individuals Suffering From Coronary Artery Disease
por: Mishra, Nitesh, et al.
Publicado: (2019)

Increased Expression of Complement Regulators CD55 and CD59 on Peripheral Blood Cells in Patients with EAHEC O104:H4 Infection
por: Dammermann, Werner, et al.
Publicado: (2013)

CD55 and CD59 expression protects HER2-overexpressing breast cancer cells from trastuzumab-induced complement-dependent cytotoxicity
por: Wang, Yu, et al.
Publicado: (2017)

Value of CD16/CD66b/CD45 in comparison to CD55/CD59/CD45 in diagnosis of paroxysmal nocturnal haemoglobinuria: An Indian experience
por: Kotru, Mrinalini, et al.
Publicado: (2017)

Molecular pathogenesis of human CD59 deficiency
por: Karbian, Netanel, et al.
Publicado: (2018)

Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1
Publicado: (1995)

Beyond the Role of CD55 as a Complement Component
por: Dho, So Hee, et al.
Publicado: (2018)

Analysis of Swine Leukocyte Antigen Haplotypes in Yucatan Miniature Pigs Used as Biomedical Model Animal
por: Choi, Nu-Ri, et al.
Publicado: (2016)

The immunohistochemical analysis of membrane-bound CD55, CD59 and fluid-phase FH and FH-like complement inhibitors in cancers of ovary and corpus uteri origin
por: Kapka-Skrzypczak, Lucyna, et al.
Publicado: (2015)

Extracellular Vesicles Isolated from Plasma of Multiple Myeloma Patients Treated with Daratumumab Express CD38, PD-L1, and the Complement Inhibitory Proteins CD55 and CD59
por: Brennan, Kieran, et al.
Publicado: (2022)

Anaemia & expression levels of CD35, CD55 & CD59 on red blood cells in Plasmodium falciparum malaria patients from India
por: Mahajan, R.C., et al.
Publicado: (2011)

Generation of 1E8 Single Chain Fv-Fc Construct Against Human CD59
por: Hong, Jeong-Won, et al.
Publicado: (2012)

Subcutaneous Injection Performance in Yucatan Miniature Pigs with and without Human Hyaluronidase and Auto-injector Tolerability in Humans
por: Shi, Galen H., et al.
Publicado: (2021)

NANOG confers resistance to complement-dependent cytotoxicity in immune-edited tumor cells through up-regulating CD59
por: Son, Sung Wook, et al.
Publicado: (2022)

Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59
por: Johnson, Steven, et al.
Publicado: (2013)

Effects of Trichostatin A on In vitro Development of Porcine Embryos Derived from Somatic Cell Nuclear Transfer
por: Jeong, Yeon Ik, et al.
Publicado: (2013)

A Systemic Lupus Erythematosus Patient with Isolated Neutropenia and Diminished Expression of CD55 and CD59 Similar to Paroxysmal Nocturnal Hemoglobinuria
por: Yıldız, Abdülkerim, et al.
Publicado: (2014)

CD5 Expression Dynamically Changes During the Differentiation of Human CD8(+) T Cells Predicting Clinical Response to Immunotherapy
por: Kim, Young Ju, et al.
Publicado: (2023)

Pharmacokinetic Compatibility Study of Lidocaine with EXPAREL in Yucatan Miniature Pigs
por: Richard, Brigitte M., et al.
Publicado: (2011)

Incorporation of CD55 into the Zika Viral Envelope Contributes to Its Stability against Human Complement
por: Malekshahi, Zahra, et al.
Publicado: (2021)

The presence of CD55- and/or CD59-deficient erythrocytic populations in patients with rheumatic diseases reflects an immune-mediated bone-marrow derived phenomenon
por: Asimakopoulos, John V., et al.
Publicado: (2014)

Ginseng Gintonin Contains Ligands for GPR40 and GPR55
por: Cho, Yeon-Jin, et al.
Publicado: (2020)

Physiologic relevance of the membrane attack complex inhibitory protein CD59 in human seminal plasma: CD59 is present on extracellular organelles (prostasomes), binds cell membranes, and inhibits complement- mediated lysis
Publicado: (1993)

Targeted Disruption of LDLR Causes Hypercholesterolemia and Atherosclerosis in Yucatan Miniature Pigs
por: Davis, Bryan T., et al.
Publicado: (2014)

Downregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: implications for trastuzumab-based immunotherapy
por: Bellone, S, et al.
Publicado: (2012)

Formaldehyde exposure induces differentiation of regulatory T cells via the NFAT-mediated T cell receptor signalling pathway in Yucatan minipigs
por: Park, Jeongsik, et al.
Publicado: (2022)

Toxicity of diclofenac sodium salt in Yucatan minipigs (Sus scrofa) following 4 weeks of daily intramuscular administration
por: Kim, Hyung-Sun, et al.
Publicado: (2021)

Mapping the Active Site of CD59
por: Yu, Jinghua, et al.
Publicado: (1997)

The Cytolytic Activity of Vaginolysin Strictly Depends on Cholesterol and Is Potentiated by Human CD59
por: Zilnyte, Milda, et al.
Publicado: (2015)

Blockade of complement activation in bullous pemphigoid by using recombinant CD55-CD46 fusion protein
por: Qiao, Pei, et al.
Publicado: (2021)

Inhibition of complement activation by CD55 overexpression in human induced pluripotent stem cell derived kidney organoids
por: Gaykema, Lonneke H., et al.
Publicado: (2023)

Genome analysis of Yucatan miniature pigs to assess their potential as biomedical model animals
por: Kwon, Dae-Jin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4h883g8b90qvla1sp0s38ffu5c