TGF-β Signaling Is Often Attenuated during Hepatotumorigenesis, but Is Retained for the Malignancy of Hepatocellular Carcinoma Cells

The role of transforming growth factor-beta (TGF-β) signaling in hepatocarcinogenesis remains controversial. We aimed to reveal TGF-β signaling status in human and murine tissues of hepatocellular carcinoma (HCC) and the mechanisms that mediate TGF-β’s role in regulating HCC malignancy. Here, TGF-β...

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Detalles Bibliográficos
Autores principales: Mu, Xiaoxin, Lin, Shu, Yang, Junhua, Chen, Chen, Chen, Yun, Herzig, Maryanne C., Washburn, Kenneth, Halff, Glenn A., Walter, Christi A., Sun, Beicheng, Sun, Lu-Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660330/
https://www.ncbi.nlm.nih.gov/pubmed/23704908
http://dx.doi.org/10.1371/journal.pone.0063436

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