Cargando…

Age-Specific Gene Expression Signatures for Breast Tumors and Cross-Species Conserved Potential Cancer Progression Markers in Young Women

Breast cancer in young women is more aggressive with a poorer prognosis and overall survival compared to older women diagnosed with the disease. Despite recent research, the underlying biology and molecular alterations that drive the aggressive nature of breast tumors associated with breast cancer i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Colak, Dilek, Nofal, Asmaa, AlBakheet, AlBandary, Nirmal, Maimoona, Jeprel, Hatim, Eldali, Abdelmoneim, AL-Tweigeri, Taher, Tulbah, Asma, Ajarim, Dahish, Malik, Osama Al, Inan, Mehmet S., Kaya, Namik, Park, Ben H., Bin Amer, Suad M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660335/ https://www.ncbi.nlm.nih.gov/pubmed/23704896 http://dx.doi.org/10.1371/journal.pone.0063204

Ejemplares similares

Obesity is a significant risk factor for breast cancer in Arab women
por: Elkum, Naser, et al.
Publicado: (2014)

Global Transcriptional Profiling of Granulosa Cells from Polycystic Ovary Syndrome Patients: Comparative Analyses of Patients with or without History of Ovarian Hyperstimulation Syndrome Reveals Distinct Biomarkers and Pathways
por: Daghestani, Maha H., et al.
Publicado: (2022)

Fascin Is a Key Regulator of Breast Cancer Invasion That Acts via the Modification of Metastasis-Associated Molecules
por: Al-Alwan, Monther, et al.
Publicado: (2011)

Weekly Paclitaxel given concurrently with Durvalumab has a favorable safety profile in triple-negative metastatic breast cancer
por: Ghebeh, Hazem, et al.
Publicado: (2021)

Being 40 or younger is an independent risk factor for relapse in operable breast cancer patients: The Saudi Arabia experience
por: Elkum, Naser, et al.
Publicado: (2007)

Impact of Pathologic Complete Response following Neoadjuvant Chemotherapy ± Trastuzumab in Locally Advanced Breast Cancer
por: Al-Tweigeri, Taher, et al.
Publicado: (2021)

Detailed genetic and clinical analysis of a novel de novo variant in HPRT1: Case report of a female patient from Saudi Arabia with Lesch–Nyhan syndrome
por: AlBakheet, Albandary, et al.
Publicado: (2023)

Induction of cell proliferation in old rat liver can reset certain gene expression levels characteristic of old liver to those associated with young liver
por: Chishti, Muhammad A., et al.
Publicado: (2012)

Clinical Identification of Dysregulated Circulating microRNAs and Their Implication in Drug Response in Triple Negative Breast Cancer (TNBC) by Target Gene Network and Meta-Analysis
por: Qattan, Amal, et al.
Publicado: (2021)

Breast stromal fibroblasts from histologically normal surgical margins are pro-carcinogenic
por: Al-Rakan, Maha A, et al.
Publicado: (2013)

Ancient founder mutation in RUBCN: a second unrelated family confirms Salih ataxia (SCAR15)
por: Seidahmed, Mohammed Z., et al.
Publicado: (2020)

High DNMT1 Expression in Stromal Fibroblasts Promotes Angiogenesis and Unfavorable Outcome in Locally Advanced Breast Cancer Patients
por: Al-Kharashi, Layla A., et al.
Publicado: (2022)

Bidirectional crosstalk between PD-L1 expression and epithelial to mesenchymal transition: Significance in claudin-low breast cancer cells
por: Alsuliman, Abdullah, et al.
Publicado: (2015)

A Novel GEMIN4 Variant in a Consanguineous Family Leads to Neurodevelopmental Impairment with Severe Microcephaly, Spastic Quadriplegia, Epilepsy, and Cataracts
por: Aldhalaan, Hesham, et al.
Publicado: (2021)

Single-Institute Review of HER-2/Neu-Positive Invasive Lobular Breast Carcinoma in an Arab Population
por: Osmani, Asif Husain, et al.
Publicado: (2021)

A Novel Homozygous Founder Variant of RTN4IP1 in Two Consanguineous Saudi Families
por: Aldosary, Mazhor, et al.
Publicado: (2022)

β1 Integrin is essential for fascin‐mediated breast cancer stem cell function and disease progression
por: Barnawi, Rayanah, et al.
Publicado: (2019)

p16(INK4A) Positively Regulates Cyclin D1 and E2F1 through Negative Control of AUF1
por: Al-Khalaf, Huda H., et al.
Publicado: (2011)

The molecular significance of methylated BRCA1 promoter in white blood cells of cancer-free females
por: Al-Moghrabi, Nisreen, et al.
Publicado: (2014)

Association Between Neutrophil-Lymphocyte Ratio and Oncotype Dx Recurrence Score in Early-Stage Hormonal Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer
por: Alshamsan, Bader, et al.
Publicado: (2021)

Integrative and comparative genomics analysis of early hepatocellular carcinoma differentiated from liver regeneration in young and old
por: Colak, Dilek, et al.
Publicado: (2010)

Higher PD-L1 Immunohistochemical Detection Signal in Frozen Compared to Matched Paraffin-Embedded Formalin-Fixed Tissues
por: Ghebeh, Hazem, et al.
Publicado: (2021)

Clinical and functional significance of tumor/stromal ATR expression in breast cancer patients
por: Al-Ansari, Mysoon M., et al.
Publicado: (2020)

Association Between Obesity and Clinicopathological Profile of Patients with Newly Diagnosed Non-Metastatic Breast Cancer in Saudi Arabia
por: Alshamsan, Bader, et al.
Publicado: (2022)

SLC25A42‐associated mitochondrial encephalomyopathy: Report of additional founder cases and functional characterization of a novel deletion
por: Aldosary, Mazhor, et al.
Publicado: (2021)

Oral Health-Related Quality of Life (OHRQoL) of Children with Down Syndrome and Their Families: A Cross-Sectional Study
por: AlJameel, AlBandary Hassan, et al.
Publicado: (2021)

Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway
por: Ghebeh, H, et al.
Publicado: (2014)

Identification of novel genomic imbalances in Saudi patients with congenital heart disease
por: Al-Hassnan, Zuhair N., et al.
Publicado: (2018)

High AUF1 level in stromal fibroblasts promotes carcinogenesis and chemoresistance and predicts unfavorable prognosis among locally advanced breast cancer patients
por: Al-Tweigeri, Taher, et al.
Publicado: (2022)

Behavior and Outcomes of Pregnancy Associated Breast Cancer
por: Suleman, Kausar, et al.
Publicado: (2019)

First report of two successive deletions on chromosome 15q13 cytogenetic bands in a boy and girl: additional data to 15q13.3 syndrome with a report of high IQ patient
por: Alsagob, Maysoon, et al.
Publicado: (2019)

Identification of novel BRCA founder mutations in Middle Eastern breast cancer patients using capture and Sanger sequencing analysis
por: Bu, Rong, et al.
Publicado: (2016)

Overexpression of PARP is an independent prognostic marker for poor survival in Middle Eastern breast cancer and its inhibition can be enhanced with embelin co-treatment
por: Siraj, Abdul Khalid, et al.
Publicado: (2018)

Complete Response of Chemo-Refractory Metastatic Metaplastic Breast Cancer to Paclitaxel-Immunotherapy Combination
por: Al Sayed, Adher D., et al.
Publicado: (2019)

Impact of DMFT, PUFA, DAI, and TDIs on Oral Health-Related Quality of Life (OHRQoL) Among Foundling, Delinquent, and Mainstream School Children: A Prilimenary Study
por: Alsaif, Abdulaziz Abdullah, et al.
Publicado: (2022)

Clinical, radiological, and genetic characterization of SLC13A5 variants in Saudi families: Genotype phenotype correlation and brief review of the literature
por: AlQudairy, Hanan, et al.
Publicado: (2023)

High Expression of Cyclin D1 is an Independent Marker for Favorable Prognosis in Middle Eastern Breast Cancer
por: Siraj, Abdul K, et al.
Publicado: (2021)

FOXP3(+ )T(regs )and B7-H1(+)/PD-1(+ )T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy
por: Ghebeh, Hazem, et al.
Publicado: (2008)

Down syndrome and oral health: mothers’ perception on their children’s oral health and its impact
por: AlJameel, AlBandary H., et al.
Publicado: (2020)

ALK alteration is a frequent event in aggressive breast cancers
por: Siraj, Abdul K., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_1uc3o0371msmqic6u2a8t65kt2