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Identification of Antithrombin-Modulating Genes. Role of LARGE, a Gene Encoding a Bifunctional Glycosyltransferase, in the Secretion of Proteins?

The haemostatic relevance of antithrombin together with the low genetic variability of SERPINC1, and the high heritability of plasma levels encourage the search for modulating genes. We used a hypothesis-free approach to identify these genes, evaluating associations between plasma antithrombin and 3...

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Detalles Bibliográficos
Autores principales:	de la Morena-Barrio, María Eugenia, Buil, Alfonso, Antón, Ana Isabel, Martínez-Martínez, Irene, Miñano, Antonia, Gutiérrez-Gallego, Ricardo, Navarro-Fernández, José, Aguila, Sonia, Souto, Juan Carlos, Vicente, Vicente, Soria, José Manuel, Corral, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660365/ https://www.ncbi.nlm.nih.gov/pubmed/23705025 http://dx.doi.org/10.1371/journal.pone.0064998

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