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Rapid Countermeasure Discovery against Francisella tularensis Based on a Metabolic Network Reconstruction
In the future, we may be faced with the need to provide treatment for an emergent biological threat against which existing vaccines and drugs have limited efficacy or availability. To prepare for this eventuality, our objective was to use a metabolic network-based approach to rapidly identify potent...
Autores principales: | Chaudhury, Sidhartha, Abdulhameed, Mohamed Diwan M., Singh, Narender, Tawa, Gregory J., D’haeseleer, Patrik M., Zemla, Adam T., Navid, Ali, Zhou, Carol E., Franklin, Matthew C., Cheung, Jonah, Rudolph, Michael J., Love, James, Graf, John F., Rozak, David A., Dankmeyer, Jennifer L., Amemiya, Kei, Daefler, Simon, Wallqvist, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660459/ https://www.ncbi.nlm.nih.gov/pubmed/23704901 http://dx.doi.org/10.1371/journal.pone.0063369 |
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