Evolution of Smooth Tubercle Bacilli PE and PE_PGRS Genes: Evidence for a Prominent Role of Recombination and Imprint of Positive Selection

BACKGROUND: PE and PE_PGRS are two mycobateria-restricted multigene families encoding membrane associated and secreted proteins that have expanded mainly in the pathogenic species, notably the Mycobacterium tuberculosis complex (MTBC). Several lines of evidence attribute to PE and PE_PGRS genes crit...

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Detalles Bibliográficos
Autores principales: Namouchi, Amine, Karboul, Anis, Fabre, Michel, Gutierrez, Maria Cristina, Mardassi, Helmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660525/
https://www.ncbi.nlm.nih.gov/pubmed/23705005
http://dx.doi.org/10.1371/journal.pone.0064718

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