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Protection against Myocardial Ischemia-Reperfusion Injury at Onset of Type 2 Diabetes in Zucker Diabetic Fatty Rats Is Associated with Altered Glucose Oxidation
BACKGROUND: Inhibition of glucose oxidation during initial reperfusion confers protection against ischemia-reperfusion (IR) injury in the heart. Mitochondrial metabolism is altered with progression of type 2 diabetes (T2DM). We hypothesized that the metabolic alterations present at onset of T2DM ind...
Autores principales: | Povlsen, Jonas Agerlund, Løfgren, Bo, Dalgas, Christian, Birkler, Rune Isak Dupont, Johannsen, Mogens, Støttrup, Nicolaj Brejnholt, Bøtker, Hans Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660588/ https://www.ncbi.nlm.nih.gov/pubmed/23704975 http://dx.doi.org/10.1371/journal.pone.0064093 |
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