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Brevilin A, a Novel Natural Product, Inhibits Janus Kinase Activity and Blocks STAT3 Signaling in Cancer Cells
Signal abnormalities in human cells usually cause unexpected consequences for individual health. We focus on these kinds of events involved in JAK-STAT signal pathways, especially the ones triggered by aberrant activated STAT3, an oncoprotein which participates in essential processes of cell surviva...
Autores principales: | Chen, Xing, Du, Yuping, Nan, Jing, Zhang, Xinxin, Qin, Xiaodong, Wang, Yuxin, Hou, Jianwen, Wang, Qin, Yang, Jinbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660600/ https://www.ncbi.nlm.nih.gov/pubmed/23704931 http://dx.doi.org/10.1371/journal.pone.0063697 |
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