Characterization of Cognitive Deficits in Rats Overexpressing Human Alpha-Synuclein in the Ventral Tegmental Area and Medial Septum Using Recombinant Adeno-Associated Viral Vectors

Intraneuronal inclusions containing alpha-synuclein (a-syn) constitute one of the pathological hallmarks of Parkinson's disease (PD) and are accompanied by severe neurodegeneration of A9 dopaminergic neurons located in the substantia nigra. Although to a lesser extent, A10 dopaminergic neurons...

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Detalles Bibliográficos
Autores principales: Hall, Hélène, Jewett, Michael, Landeck, Natalie, Nilsson, Nathalie, Schagerlöf, Ulrika, Leanza, Giampiero, Kirik, Deniz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660601/
https://www.ncbi.nlm.nih.gov/pubmed/23705016
http://dx.doi.org/10.1371/journal.pone.0064844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660601/
https://www.ncbi.nlm.nih.gov/pubmed/23705016
http://dx.doi.org/10.1371/journal.pone.0064844

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