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A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans

Regulation of animal development in response to nutritional cues is an intensely studied problem related to disease and aging. While extensive studies indicated roles of the Target of Rapamycin (TOR) in sensing certain nutrients for controlling growth and metabolism, the roles of fatty acids and lip...

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Detalles Bibliográficos
Autores principales: Zhu, Huanhu, Shen, Huali, Sewell, Aileen K, Kniazeva, Marina, Han, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660743/
https://www.ncbi.nlm.nih.gov/pubmed/23705068
http://dx.doi.org/10.7554/eLife.00429