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Orexin receptor-1 mediates brown fat developmental differentiation

Orexin A (OX) is a small excitatory neuropeptide hormone that stimulates feeding, wakefulness and energy expenditure via a pair of G-coupled protein receptors, namely orexin receptor-1 (OXR1) and orexin receptor-2 (OXR2). OX-deficient mice are sensitive to obesity despite being hypophagic. The obeso...

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Detalles Bibliográficos
Autores principales: Sellayah, Dyan, Sikder, Devanjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661127/
https://www.ncbi.nlm.nih.gov/pubmed/23700511
http://dx.doi.org/10.4161/adip.18965