COX2 regulation of breast cancer bone metastasis

High expression levels of cyclooxygenase 2 expression and infiltration by regulatory T cells (Tregs) are often associated with tumor progression. We have recently reported a prostaglandin E(2) (PGE(2))-dependent recruitment of Tregs to the tumor, suggesting that targeting specific PGE(2) receptors m...

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Detalles Bibliográficos
Autores principales: Karavitis, John, Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661150/
https://www.ncbi.nlm.nih.gov/pubmed/23802065
http://dx.doi.org/10.4161/onci.23129
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author Karavitis, John
Zhang, Ming
author_facet Karavitis, John
Zhang, Ming
author_sort Karavitis, John
collection PubMed
description High expression levels of cyclooxygenase 2 expression and infiltration by regulatory T cells (Tregs) are often associated with tumor progression. We have recently reported a prostaglandin E(2) (PGE(2))-dependent recruitment of Tregs to the tumor, suggesting that targeting specific PGE(2) receptors may constitute a valuable approach to ablate the immuno-editing that occurs along with disease progression.
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spelling pubmed-36611502013-06-25 COX2 regulation of breast cancer bone metastasis Karavitis, John Zhang, Ming Oncoimmunology Author's View High expression levels of cyclooxygenase 2 expression and infiltration by regulatory T cells (Tregs) are often associated with tumor progression. We have recently reported a prostaglandin E(2) (PGE(2))-dependent recruitment of Tregs to the tumor, suggesting that targeting specific PGE(2) receptors may constitute a valuable approach to ablate the immuno-editing that occurs along with disease progression. Landes Bioscience 2013-03-01 2013-03-01 /pmc/articles/PMC3661150/ /pubmed/23802065 http://dx.doi.org/10.4161/onci.23129 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Karavitis, John
Zhang, Ming
COX2 regulation of breast cancer bone metastasis
title COX2 regulation of breast cancer bone metastasis
title_full COX2 regulation of breast cancer bone metastasis
title_fullStr COX2 regulation of breast cancer bone metastasis
title_full_unstemmed COX2 regulation of breast cancer bone metastasis
title_short COX2 regulation of breast cancer bone metastasis
title_sort cox2 regulation of breast cancer bone metastasis
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661150/
https://www.ncbi.nlm.nih.gov/pubmed/23802065
http://dx.doi.org/10.4161/onci.23129
work_keys_str_mv AT karavitisjohn cox2regulationofbreastcancerbonemetastasis
AT zhangming cox2regulationofbreastcancerbonemetastasis

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