Bacteria evade immune recognition via TLR13 and binding of their 23S rRNA by MLS antibiotics by the same mechanisms

The immune system recognizes pathogens and other danger by means of pattern recognition receptors. Recently, we have demonstrated that the orphan Toll-like receptor 13 (TLR13) senses a defined sequence of the bacterial rRNA and that bacteria use specific mechanisms to evade macrolide lincosamide str...

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Detalles Bibliográficos
Autores principales: Hochrein, Hubertus, Kirschning, Carsten J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661153/
https://www.ncbi.nlm.nih.gov/pubmed/23802068
http://dx.doi.org/10.4161/onci.23141
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author Hochrein, Hubertus
Kirschning, Carsten J.
author_facet Hochrein, Hubertus
Kirschning, Carsten J.
author_sort Hochrein, Hubertus
collection PubMed
description The immune system recognizes pathogens and other danger by means of pattern recognition receptors. Recently, we have demonstrated that the orphan Toll-like receptor 13 (TLR13) senses a defined sequence of the bacterial rRNA and that bacteria use specific mechanisms to evade macrolide lincosamide streptogramin (MLS) antibiotics detection via TLR13.
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spelling pubmed-36611532013-06-25 Bacteria evade immune recognition via TLR13 and binding of their 23S rRNA by MLS antibiotics by the same mechanisms Hochrein, Hubertus Kirschning, Carsten J. Oncoimmunology Author's View The immune system recognizes pathogens and other danger by means of pattern recognition receptors. Recently, we have demonstrated that the orphan Toll-like receptor 13 (TLR13) senses a defined sequence of the bacterial rRNA and that bacteria use specific mechanisms to evade macrolide lincosamide streptogramin (MLS) antibiotics detection via TLR13. Landes Bioscience 2013-03-01 2013-03-01 /pmc/articles/PMC3661153/ /pubmed/23802068 http://dx.doi.org/10.4161/onci.23141 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Hochrein, Hubertus
Kirschning, Carsten J.
Bacteria evade immune recognition via TLR13 and binding of their 23S rRNA by MLS antibiotics by the same mechanisms
title Bacteria evade immune recognition via TLR13 and binding of their 23S rRNA by MLS antibiotics by the same mechanisms
title_full Bacteria evade immune recognition via TLR13 and binding of their 23S rRNA by MLS antibiotics by the same mechanisms
title_fullStr Bacteria evade immune recognition via TLR13 and binding of their 23S rRNA by MLS antibiotics by the same mechanisms
title_full_unstemmed Bacteria evade immune recognition via TLR13 and binding of their 23S rRNA by MLS antibiotics by the same mechanisms
title_short Bacteria evade immune recognition via TLR13 and binding of their 23S rRNA by MLS antibiotics by the same mechanisms
title_sort bacteria evade immune recognition via tlr13 and binding of their 23s rrna by mls antibiotics by the same mechanisms
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661153/
https://www.ncbi.nlm.nih.gov/pubmed/23802068
http://dx.doi.org/10.4161/onci.23141
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