Regulation of DC development and DC-mediated T-cell immunity via CISH

Cytokine inducible SH2-containing protein (CISH) plays a crucial role in type 1 dendritic cell (DC) development as well as in the DC-mediated activation of cytotoxic T lymphocytes (CTLs). CISH expression at late DC developmental stages shuts down the proliferation of DC progenitors by negatively reg...

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Detalles Bibliográficos
Autores principales: Miah, Mohammad Alam, Bae, Yong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661167/
https://www.ncbi.nlm.nih.gov/pubmed/23802082
http://dx.doi.org/10.4161/onci.23404
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author Miah, Mohammad Alam
Bae, Yong-Soo
author_facet Miah, Mohammad Alam
Bae, Yong-Soo
author_sort Miah, Mohammad Alam
collection PubMed
description Cytokine inducible SH2-containing protein (CISH) plays a crucial role in type 1 dendritic cell (DC) development as well as in the DC-mediated activation of cytotoxic T lymphocytes (CTLs). CISH expression at late DC developmental stages shuts down the proliferation of DC progenitors by negatively regulating signal transducer and activator of transcription 5 (STAT5) and facilitates the differentiation of DCs into potent stimulators of CTLs.
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spelling pubmed-36611672013-06-25 Regulation of DC development and DC-mediated T-cell immunity via CISH Miah, Mohammad Alam Bae, Yong-Soo Oncoimmunology Author's View Cytokine inducible SH2-containing protein (CISH) plays a crucial role in type 1 dendritic cell (DC) development as well as in the DC-mediated activation of cytotoxic T lymphocytes (CTLs). CISH expression at late DC developmental stages shuts down the proliferation of DC progenitors by negatively regulating signal transducer and activator of transcription 5 (STAT5) and facilitates the differentiation of DCs into potent stimulators of CTLs. Landes Bioscience 2013-03-01 2013-03-01 /pmc/articles/PMC3661167/ /pubmed/23802082 http://dx.doi.org/10.4161/onci.23404 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Miah, Mohammad Alam
Bae, Yong-Soo
Regulation of DC development and DC-mediated T-cell immunity via CISH
title Regulation of DC development and DC-mediated T-cell immunity via CISH
title_full Regulation of DC development and DC-mediated T-cell immunity via CISH
title_fullStr Regulation of DC development and DC-mediated T-cell immunity via CISH
title_full_unstemmed Regulation of DC development and DC-mediated T-cell immunity via CISH
title_short Regulation of DC development and DC-mediated T-cell immunity via CISH
title_sort regulation of dc development and dc-mediated t-cell immunity via cish
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661167/
https://www.ncbi.nlm.nih.gov/pubmed/23802082
http://dx.doi.org/10.4161/onci.23404
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AT baeyongsoo regulationofdcdevelopmentanddcmediatedtcellimmunityviacish

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