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An unexpected role of neuroligin-2 in regulating KCC2 and GABA functional switch
BACKGROUND: GABA(A) receptors are ligand-gated Cl(-) channels, and the intracellular Cl(-) concentration governs whether GABA function is excitatory or inhibitory. During early brain development, GABA undergoes functional switch from excitation to inhibition: GABA depolarizes immature neurons but hy...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661362/ https://www.ncbi.nlm.nih.gov/pubmed/23663753 http://dx.doi.org/10.1186/1756-6606-6-23 |