Acute 5-HT7 receptor activation increases NMDA-evoked currents and differentially alters NMDA receptor subunit phosphorylation and trafficking in hippocampal neurons

BACKGROUND: N-methyl-D-aspartate (NMDA) receptors are regulated by several G protein-coupled receptors (GPCRs) as well as receptor tyrosine kinases. Serotonin (5-HT) type 7 receptors are expressed throughout the brain including the thalamus and hippocampus. Long-term (2–24 h) activation of 5-HT7 rec...

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Detalles Bibliográficos
Autores principales: Vasefi, Maryam S, Yang, Kai, Li, Jerry, Kruk, Jeff S, Heikkila, John J, Jackson, Michael F, MacDonald, John F, Beazely, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661375/
https://www.ncbi.nlm.nih.gov/pubmed/23672716
http://dx.doi.org/10.1186/1756-6606-6-24

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