Response to imatinib in villonodular pigmented synovitis (PVNS) resistant to nilotinib

BACKGROUND: Pigmented villonodular synovitis (PVNS) is a rare locally aggressive tumor. PVNS is characterized in most cases by a specific t(1;2) translocation, which fuses the colony stimulating factor-1 (CSF1) gene to the collagen type VIa3 (COL6A3) promoter thus leading through a paracrine effect...

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Detalles Bibliográficos
Autores principales: Stacchiotti, Silvia, Crippa, Flavio, Messina, Antonella, Pilotti, Silvana, Gronchi, Alessandro, Blay, Jean Y, Casali, Paolo G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661378/
https://www.ncbi.nlm.nih.gov/pubmed/23668619
http://dx.doi.org/10.1186/2045-3329-3-8

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