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Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells

BACKGROUND: Epidemiological studies have shown direct associations between type 2 diabetes and obesity, both conditions associated with hyperglycaemia and hyperinsulinemia, and the risk of pancreatic cancer. Up to 80% of pancreatic cancer patients present with either new-onset type 2 diabetes or imp...

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Detalles Bibliográficos
Autores principales:	Karnevi, Emelie, Said, Katarzyna, Andersson, Roland, Rosendahl, Ann H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661399/ https://www.ncbi.nlm.nih.gov/pubmed/23663483 http://dx.doi.org/10.1186/1471-2407-13-235

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