Cargando…

Genetic Variation in 15-Hydroxyprostaglandin Dehydrogenase and Colon Cancer Susceptibility

BACKGROUND: 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is a metabolic antagonist of COX-2, catalyzing the degradation of inflammation mediator prostaglandin E2 (PGE(2)) and other prostanoids. Recent studies have established the 15-PGDH gene as a colon cancer suppressor. METHODS: We evaluated 15...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thompson, Cheryl L., Fink, Stephen P., Lutterbaugh, James D., Elston, Robert C., Veigl, Martina L., Markowitz, Sanford D., Li, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661460/ https://www.ncbi.nlm.nih.gov/pubmed/23717544 http://dx.doi.org/10.1371/journal.pone.0064122

Ejemplares similares

15-Hydroxyprostaglandin dehydrogenase inhibitor prevents contrast-induced acute kidney injury
por: Kim, Byeong Woo, et al.
Publicado: (2021)

miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer
por: Monteleone, Nicholas J., et al.
Publicado: (2019)

Decreased Expression of 15-hydroxyprostaglandin Dehydrogenase in Gastric Carcinomas
por: Jang, Tae Jung, et al.
Publicado: (2008)

Relationship between 15-hydroxyprostaglandin dehydrogenase and gastric adenocarcinoma
por: Kang, Jae Hyun, et al.
Publicado: (2014)

Downregulation of 15-hydroxyprostaglandin dehydrogenase in hormone-resistant breast cancer
por: Cummings, M, et al.
Publicado: (2008)

15-Hydroxyprostaglandin dehydrogenase as a marker in colon carcinogenesis: analysis of the prostaglandin pathway in human colonic tissue
por: Yang, Dong-Hoon, et al.
Publicado: (2017)

15-Hydroxyprostaglandin Dehydrogenase Is a Predictor of Stroke-Associated Pneumonia
por: Xu, Yunfei, et al.
Publicado: (2022)

Role of 15-hydroxyprostaglandin dehydrogenase down-regulation on the prognosis of hepatocellular carcinoma
por: Yang, Jee Eun, et al.
Publicado: (2014)

Tumour suppressor 15-hydroxyprostaglandin dehydrogenase induces differentiation in colon cancer via GLI1 inhibition
por: Satapathy, Shakti Ranjan, et al.
Publicado: (2020)

Prognostic Implication of 15-Hydroxyprostaglandin Dehydrogenase Down-Regulation in Patients with Colorectal Cancer
por: Kang, Pil Sung, et al.
Publicado: (2012)

15-Hydroxyprostaglandin dehydrogenase is upregulated by hydroxychloroquine in rheumatoid arthritis fibroblast-like synoviocytes
por: KIM, HAK-JAE, et al.
Publicado: (2015)

Sex Differential in 15‐Hydroxyprostaglandin Dehydrogenase Levels in the Lumen of Human Intracranial Aneurysms
por: Chalouhi, Nohra, et al.
Publicado: (2017)

In-vitro Wound Healing Effect of 15-Hydroxyprostaglandin Dehydrogenase Inhibitor from Plant
por: Karna, Sandeep
Publicado: (2017)

15-hydroxyprostaglandin dehydrogenase (15-PGDH) prevents lipopolysaccharide (LPS)-induced acute liver injury
por: Yao, Lu, et al.
Publicado: (2017)

15-Hydroxyprostaglandin Dehydrogenase in Colorectal Mucosa as a Potential Biomarker for Predicting Colorectal Neoplasms
por: Lee, Hyo Jeong, et al.
Publicado: (2013)

miR-620 promotes tumor radioresistance by targeting 15-hydroxyprostaglandin dehydrogenase (HPGD)
por: Huang, Xiaoyong, et al.
Publicado: (2015)

Effect of 15-hydroxyprostaglandin dehydrogenase gene on the proliferation of gastric cancer cell murine forestomach carcinoma
por: LI, LIHUA, et al.
Publicado: (2014)

Early pregnancy loss in 15-hydroxyprostaglandin dehydrogenase knockout (15-HPGD(−/−)) mice due to requirement for embryo 15-HPGD activity
por: Roizen, Jeffrey D., et al.
Publicado: (2019)

11-Oxoeicosatetraenoic Acid Is a Cyclooxygenase-2/15-Hydroxyprostaglandin Dehydrogenase-Derived Antiproliferative Eicosanoid
por: Liu, Xiaojing, et al.
Publicado: (2011)

MicroRNA-21 induces loss of 15-hydroxyprostaglandin dehydrogenase in early gastric tubular adenocarcinoma
por: Park, Young Soo, et al.
Publicado: (2018)

Expression of 15-hydroxyprostaglandin dehydrogenase and cyclooxygenase-2 in non-small cell lung cancer: Correlations with angiogenesis and prognosis
por: LI, YING, et al.
Publicado: (2014)

A potential anti-tumor effect of leukotriene C(4) through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells
por: Mehdawi, Lubna M., et al.
Publicado: (2017)

Smad4-deficient T cells promote colitis-associated colon cancer via an IFN-γ-dependent suppression of 15-hydroxyprostaglandin dehydrogenase
por: Choi, Sung Hee, et al.
Publicado: (2022)

High-Affinity Inhibitors of Human NAD(+)-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships
por: Niesen, Frank H., et al.
Publicado: (2010)

Downregulation of 15‐hydroxyprostaglandin dehydrogenase by interleukin‐1β from activated macrophages leads to poor prognosis in pancreatic cancer
por: Arima, Kota, et al.
Publicado: (2018)

Compound Heterozygous Pathogenic Variants of the 15-Hydroxyprostaglandin Dehydrogenase Gene in a Patient With Hypertrophic Osteoarthropathy: First Case in Korea
por: Ryu, Mi Ra, et al.
Publicado: (2019)

Structural Insights into Novel 15-Prostaglandin Dehydrogenase Inhibitors
por: Mallipeddi, Prema L., et al.
Publicado: (2021)

GNAS Mutations Identify a Set of Right-Sided, RAS Mutant, Villous Colon Cancers
por: Fecteau, Ryan E., et al.
Publicado: (2014)

Rebamipide, a mucoprotective drug, inhibits NSAIDs-induced gastric mucosal injury: possible involvement of the downregulation of 15-hydroxyprostaglandin dehydrogenase
por: Tanigawa, Tetsuya, et al.
Publicado: (2011)

Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERα-positive breast cancer
por: Volpato, Milene, et al.
Publicado: (2020)

MicroRNA-21 regulates prostaglandin E2 signaling pathway by targeting 15-hydroxyprostaglandin dehydrogenase in tongue squamous cell carcinoma
por: He, Qianting, et al.
Publicado: (2016)

The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia
por: Pang, Huiyuan, et al.
Publicado: (2023)

15-Deoxy-Δ(12,14)-prostaglandin J(2) Upregulates the Expression of 15-Hydroxyprostaglandin Dehydrogenase by Inducing AP-1 Activation and Heme Oxygenase-1 Expression in Human Colon Cancer Cells
por: Park, Jong-Min, et al.
Publicado: (2019)

15-Deoxy-Δ(12,14)-prostaglandin J2 Upregulates the Expression of 15-Hydroxyprostaglandin Dehydrogenase by Inducing AP-1 Activation and Heme Oxygenase-1 Expression in Human Colon Cancer Cells
por: Park, Jong-Min, et al.
Publicado: (2019)

Association of 15-hydroxyprostaglandin dehydrogenate and poor prognosis of obese breast cancer patients
por: Wu, Ruxing, et al.
Publicado: (2017)

A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis
por: Markowitz, Sanford D., et al.
Publicado: (2016)

MicroRNA-218 promotes prostaglandin E2 to inhibit osteogenic differentiation in synovial mesenchymal stem cells by targeting 15-hydroxyprostaglandin dehydrogenase [NAD(+)]
por: Cong, Ruijun, et al.
Publicado: (2017)

Overexpression of 15-Hydroxyprostaglandin Dehydrogenase Inhibits A549 Lung Adenocarcinoma Cell Growth via Inducing Cell Cycle Arrest and Inhibiting Epithelial-Mesenchymal Transition
por: Wang, Weixuan, et al.
Publicado: (2021)

H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island-containing start sites
por: Balasubramanian, Dheepa, et al.
Publicado: (2012)

Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer
por: Venkitachalam, Srividya, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6fnfg9rpb9513if7tkhd769h8k