The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series

Tacrolimus (FK 506) is a macrolactam derivative with immunomodulatory and anti-inflammatory activity. Topical tacrolimus 0.03% has been used for inflammatory conditions of the anterior segment. This article adds to the literature on the off-license application of tacrolimus ointment, by describing t...

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Detalles Bibliográficos
Autores principales: Abeysiri, Poorna, Johnston, Nicholas R., Molteno, Anthony C.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661495/
https://www.ncbi.nlm.nih.gov/pubmed/23861611
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author Abeysiri, Poorna
Johnston, Nicholas R.
Molteno, Anthony C.B.
author_facet Abeysiri, Poorna
Johnston, Nicholas R.
Molteno, Anthony C.B.
author_sort Abeysiri, Poorna
collection PubMed
description Tacrolimus (FK 506) is a macrolactam derivative with immunomodulatory and anti-inflammatory activity. Topical tacrolimus 0.03% has been used for inflammatory conditions of the anterior segment. This article adds to the literature on the off-license application of tacrolimus ointment, by describing the safe and effective use of the higher strength of 0.1% topical tacrolimus skin ointment in four patients. To our knowledge this is the first report of topical tacrolimus 0.1% ointment applied to the conjunctival sac for the treatment of atopic keratoconjunctivitis, vernal keratoconjunctivitis and the post-operative management of trabeculectomy and graft rejection in steroid responders.
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spelling pubmed-36614952013-07-16 The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series Abeysiri, Poorna Johnston, Nicholas R. Molteno, Anthony C.B. Ophthalmol Eye Dis Case Report Tacrolimus (FK 506) is a macrolactam derivative with immunomodulatory and anti-inflammatory activity. Topical tacrolimus 0.03% has been used for inflammatory conditions of the anterior segment. This article adds to the literature on the off-license application of tacrolimus ointment, by describing the safe and effective use of the higher strength of 0.1% topical tacrolimus skin ointment in four patients. To our knowledge this is the first report of topical tacrolimus 0.1% ointment applied to the conjunctival sac for the treatment of atopic keratoconjunctivitis, vernal keratoconjunctivitis and the post-operative management of trabeculectomy and graft rejection in steroid responders. Libertas Academica 2010-02-23 /pmc/articles/PMC3661495/ /pubmed/23861611 Text en © 2010 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited.
spellingShingle Case Report
Abeysiri, Poorna
Johnston, Nicholas R.
Molteno, Anthony C.B.
The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title_full The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title_fullStr The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title_full_unstemmed The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title_short The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title_sort use of topical tacrolimus 0.1% skin ointment for anterior segment conditions: a case series
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661495/
https://www.ncbi.nlm.nih.gov/pubmed/23861611
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