P190B RhoGAP Overexpression in the Developing Mammary Epithelium Induces TGFβ-dependent Fibroblast Activation

Rho GTPases mediate stromal-epithelial interactions that are important for mammary epithelial cell (MEC) morphogenesis. Increased extracellular matrix (ECM) deposition and reorganization affect MEC morphogenesis in a Rho GTPase-dependent manner. Although the effects of altered ECM on MEC morphogenes...

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Detalles Bibliográficos
Autores principales: Gillette, Melissa, Bray, Kristi, Blumenthaler, Alisa, Vargo-Gogola, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661508/
https://www.ncbi.nlm.nih.gov/pubmed/23717689
http://dx.doi.org/10.1371/journal.pone.0065105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661508/
https://www.ncbi.nlm.nih.gov/pubmed/23717689
http://dx.doi.org/10.1371/journal.pone.0065105

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