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P190B RhoGAP Overexpression in the Developing Mammary Epithelium Induces TGFβ-dependent Fibroblast Activation
Rho GTPases mediate stromal-epithelial interactions that are important for mammary epithelial cell (MEC) morphogenesis. Increased extracellular matrix (ECM) deposition and reorganization affect MEC morphogenesis in a Rho GTPase-dependent manner. Although the effects of altered ECM on MEC morphogenes...
Autores principales: | Gillette, Melissa, Bray, Kristi, Blumenthaler, Alisa, Vargo-Gogola, Tracy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661508/ https://www.ncbi.nlm.nih.gov/pubmed/23717689 http://dx.doi.org/10.1371/journal.pone.0065105 |
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