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Impact of Glucocorticoid Receptor Density on Ligand-Independent Dimerization, Cooperative Ligand-Binding and Basal Priming of Transactivation: A Cell Culture Model
Glucocorticoid receptor (GR) levels vary between tissues and individuals and are altered by physiological and pharmacological effectors. However, the effects and implications of differences in GR concentration have not been fully elucidated. Using three statistically different GR concentrations in t...
Autores principales: | Robertson, Steven, Rohwer, Johann M., Hapgood, Janet P., Louw, Ann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661511/ https://www.ncbi.nlm.nih.gov/pubmed/23717665 http://dx.doi.org/10.1371/journal.pone.0064831 |
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