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Anti-inflammatory and Antihistaminic Study of a Unani Eye Drop Formulation
The Unani eye drop is an ophthalmic formulation prepared for its beneficial effects in the inflammatory and allergic conditions of the eyes. In the present study, the Unani eye drop formulation was prepared and investigated for its anti-inflammatory and antihistaminic activity, using in vivo and in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661513/ https://www.ncbi.nlm.nih.gov/pubmed/23861612 |
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author | Abdul, Latif Abdul, Razique Sukul, R.R. Nazish, Siddiqui |
author_facet | Abdul, Latif Abdul, Razique Sukul, R.R. Nazish, Siddiqui |
author_sort | Abdul, Latif |
collection | PubMed |
description | The Unani eye drop is an ophthalmic formulation prepared for its beneficial effects in the inflammatory and allergic conditions of the eyes. In the present study, the Unani eye drop formulation was prepared and investigated for its anti-inflammatory and antihistaminic activity, using in vivo and in vitro experimental models respectively. The Unani eye drop formulation exhibited significant anti-inflammatory activity in turpentine liniment-induced ocular inflammation in rabbits. The preparation also showed antihistaminic activity in isolated guinea-pig ileum. The anti-inflammatory and antihistaminic activity of eye drop may be due to presence of active ingredients in the formulation. Although there are many drugs in Unani repository which are mentioned in classical books or used in Unani clinical practice effectively in treatment of eye diseases by various Unani physicians. Inspite of the availability of vast literature, there is a dearth of commercial Unani ocular preparations. So, keeping this in mind, the eye drop formulation was prepared and its anti-inflammatory and antihistaminic activity was carried out in animal models. Thus, in view of the importance of alternative anti-inflammatory and antiallergic drugs, it becomes imperative to bring these indigenous drugs to the front foot and evaluate their activities. |
format | Online Article Text |
id | pubmed-3661513 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Libertas Academica |
record_format | MEDLINE/PubMed |
spelling | pubmed-36615132013-07-16 Anti-inflammatory and Antihistaminic Study of a Unani Eye Drop Formulation Abdul, Latif Abdul, Razique Sukul, R.R. Nazish, Siddiqui Ophthalmol Eye Dis Original Research The Unani eye drop is an ophthalmic formulation prepared for its beneficial effects in the inflammatory and allergic conditions of the eyes. In the present study, the Unani eye drop formulation was prepared and investigated for its anti-inflammatory and antihistaminic activity, using in vivo and in vitro experimental models respectively. The Unani eye drop formulation exhibited significant anti-inflammatory activity in turpentine liniment-induced ocular inflammation in rabbits. The preparation also showed antihistaminic activity in isolated guinea-pig ileum. The anti-inflammatory and antihistaminic activity of eye drop may be due to presence of active ingredients in the formulation. Although there are many drugs in Unani repository which are mentioned in classical books or used in Unani clinical practice effectively in treatment of eye diseases by various Unani physicians. Inspite of the availability of vast literature, there is a dearth of commercial Unani ocular preparations. So, keeping this in mind, the eye drop formulation was prepared and its anti-inflammatory and antihistaminic activity was carried out in animal models. Thus, in view of the importance of alternative anti-inflammatory and antiallergic drugs, it becomes imperative to bring these indigenous drugs to the front foot and evaluate their activities. Libertas Academica 2010-03-10 /pmc/articles/PMC3661513/ /pubmed/23861612 Text en © 2010 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited. |
spellingShingle | Original Research Abdul, Latif Abdul, Razique Sukul, R.R. Nazish, Siddiqui Anti-inflammatory and Antihistaminic Study of a Unani Eye Drop Formulation |
title | Anti-inflammatory and Antihistaminic Study of a Unani Eye Drop Formulation |
title_full | Anti-inflammatory and Antihistaminic Study of a Unani Eye Drop Formulation |
title_fullStr | Anti-inflammatory and Antihistaminic Study of a Unani Eye Drop Formulation |
title_full_unstemmed | Anti-inflammatory and Antihistaminic Study of a Unani Eye Drop Formulation |
title_short | Anti-inflammatory and Antihistaminic Study of a Unani Eye Drop Formulation |
title_sort | anti-inflammatory and antihistaminic study of a unani eye drop formulation |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661513/ https://www.ncbi.nlm.nih.gov/pubmed/23861612 |
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