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Regulated Expression of Lentivirus-Mediated GDNF in Human Bone Marrow-Derived Mesenchymal Stem Cells and Its Neuroprotection on Dopaminergic Cells In Vitro

Gene regulation remains one of the major challenges for gene therapy in clinical trials. In the present study, we first generated a binary tetracycline-on (Tet-On) system based on two lentivirus vectors, one expressing both human glial cell line-derived neurotrophic factor (hGDNF) and humanized reco...

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Detalles Bibliográficos
Autores principales:	Yang, Wei-Hua, Yang, Chun, Xue, Yue-Qiang, Lu, Tao, Reiser, Jakob, Zhao, Li-Ru, Duan, Wei-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661514/ https://www.ncbi.nlm.nih.gov/pubmed/23717608 http://dx.doi.org/10.1371/journal.pone.0064389

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