Cargando…
Pancreatic Islet Xenograft Survival in Mice Is Extended by a Combination of Alpha-1-Antitrypsin and Single-Dose Anti-CD4/CD8 Therapy
Clinical pancreatic islet transplantation is under evaluation for the treatment of autoimmune diabetes, yet several limitations preclude widespread use. For example, there is a critical shortage of human pancreas donors. Xenotransplantation may solve this problem, yet it evokes a rigorous immune res...
Autores principales: | Ashkenazi, Efrat, Baranovski, Boris M., Shahaf, Galit, Lewis, Eli C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661573/ https://www.ncbi.nlm.nih.gov/pubmed/23717456 http://dx.doi.org/10.1371/journal.pone.0063625 |
Ejemplares similares
-
Exploration of α1-Antitrypsin Treatment Protocol for Islet Transplantation: Dosing Plan and Route of Administration
por: Baranovski, Boris M., et al.
Publicado: (2016) -
Human α1-Antitrypsin Binds to Heat-Shock Protein gp96 and Protects from Endogenous gp96-Mediated Injury In vivo
por: Ochayon, David E., et al.
Publicado: (2013) -
T Helper Subsets, Peripheral Plasticity, and the Acute Phase Protein, α1-Antitrypsin
por: Baranovski, Boris M., et al.
Publicado: (2015) -
CD103 Expression Is Required for Destruction of Pancreatic Islet Allografts by CD8(+) T Cells
por: Feng, Ye, et al.
Publicado: (2002) -
Point Mutation of a Non-Elastase-Binding Site in Human α1-Antitrypsin Alters Its Anti-Inflammatory Properties
por: Lior, Yotam, et al.
Publicado: (2018)