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A Longitudinal Study of Cognition, Proton MR Spectroscopy and Synaptic and Neuronal Pathology in Aging Wild-type and AβPPswe-PS1dE9 Mice
Proton magnetic resonance spectroscopy ((1)H MRS) is a valuable tool in Alzheimer’s disease research, investigating the functional integrity of the brain. The present longitudinal study set out to characterize the neurochemical profile of the hippocampus, measured by single voxel (1)H MRS at 7 Tesla...
Autores principales: | Jansen, Diane, Zerbi, Valerio, Janssen, Carola I. F., Dederen, Pieter J. W. C., Mutsaers, Martina P. C., Hafkemeijer, Anne, Janssen, Anna-Lena, Nobelen, Cindy L. M., Veltien, Andor, Asten, Jack J., Heerschap, Arend, Kiliaan, Amanda J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661598/ https://www.ncbi.nlm.nih.gov/pubmed/23717459 http://dx.doi.org/10.1371/journal.pone.0063643 |
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